10.9.13

All The World's A Brain

In the operating theatre two gurneys are pulled through plastic doors, on each rests a chimp covered mostly with a white paper smock. The surgeons move about below like an orchestra preparing for a performance, checking the levels for the anaesthetic, that the surgical tools are in the correct order. Two surgeons dressed in red talk to each other before one goes over to a microphone that has been lowered into the theatre.
“Ladies and Gentlemen, thank you for coming today. My name is Dr. Aaron Blaisdell and I will be providing commentary throughout today's surgery which will be a partial brain transplant between two adult chimps. The head surgeon today is Dr. Ellen Carpenter and if anybody has any questions throughout the surgery please send us a tweet and I'll try to read out the best ones. So without further ado, doctor.” he said, gesturing towards Dr. Carpenter. The dozen doctors and nurses are in place, waiting to begin. Bill and I are sat in the observation mezzanine circling the theatre, trying to eat popcorn quietly.

The surgeons begin by standing at the top of each chimpanzee's shaved head and fastening them both into a 3-pin skull fixation device. This has a series of rings around it with measurements on, co-ordinates similar to what you'd see on globe of the Earth so that the surgeons know where they are poking around. Dr. Blaisdell begins to talk.
“Craniotomy is one of the more complex subjects in surgery. We can make guesses as to what certain areas of the brain do, though it's similar to guessing the purpose and structure of internal organs of something you haven't seen the inside of. Still, we know more now than we did last week, and this particular surgery could be very valuable in the future.
The patients chosen are a pair of identical twins, the ideal candidates for any kind of organ transplant. Today we will be excising the left hemisphere of each chimpanzee and fitting in it's twins. We'll be leaving the brain stem intact, just as you would when grafting a plant cutting onto a larger plant, though everything else will be moved.” he said. We continue to watch as the surgeons begin to make the first skin incision around each chimp's head.
“I dunno if I can watch this.” says Bill. He's looking a little pale.
“Relax, you've seen the Saw films, right?”
“But...but this is for real.”
“Exactly. Relax.”

Next comes the drilling of small burrs all the way around the skull, followed by the craniotome sawing neatly the precise line needed to lift off the cranium lid.
“Just as identical twins have nonidentical fingerprints, they also don't share the patterns of sulci and gyrus.” said Dr. Blaisdell. High above the operating theatre a screen is turned on, showing the view from a head-mounted camera Dr. Carpenter was wearing. She cut open the dura matter with a pair of surgical scissors to reveal surface of the neocortex, labyrinth-like in it's many folds of grey matter. I begin to sketch, partly what is going on beneath me, partly some political cartoons satirizing the response to the Syrian gas attack.
“In the 1940s a procedure was invented that cut the corpus callosum in order to treat epileptic patients. It improved their epilepsy but patients were otherwise mentally stable, which is surprising to say they severed some 300 million nerve fibres. We've had to manufacture an artificial corpus callosum for this procedure in order to link both hemispheres once the transplant is done. Though the patients can survive with a split brain, we think it's best to get the procedure as accurate as possible.” he said, holding up what looked like two CD's. On the operating table meanwhile the left hemisphere of one of the chimpanzee's was removed and quickly placed into a chemical bath whilst Dr. Carpenter quickly used an ultrasonic aspirator on the brain of it's twin.

“We just got a tweet asking us why only transplant one hemisphere. Perhaps you'd like to answer that Dr. Carpenter?” said Blaisdell as he moved towards the surgeon and held a microphone close to her face. Her voice was slightly muffled through the surgical mask.
“To start with we are attempting one hemisphere, if successful, we'll transplant the right hemisphere in a few weeks time. I hypothesise that a brain transplant is extensively traumatic to both the nervous system and the psychology of the patient. This way the brain has a way of synchronizing itself in it's new environment, getting used to it's endocrine system, body image and so on.”
“Thank you. Dr. Carpenter just mentioned the psychology of undergoing a brain transplant, which in itself will be an entirely new field of study. Through this operation we are splitting the mind, inducing schizophrenia literally.” he said. There were a few laughs from the psychologists in the mezzanine.
“The patients have both been given a course of immunosuppressants in order to combat graft-versus-host, whilst also being administered a series of psychoactive drugs to encourage a state of temporary dissociation, mainly ketamine. Think of it similar to how you might change the furniture around in somebodies house. If you simply did it whilst they slept, they would quickly notice upon waking up. Whilst if you had been giving them a course of drugs in the previous and following weeks, they may be less inclined to either notice or become anxious about it.”
I watch as they attach the artificial corpus callosum onto the right hemisphere before sliding the rest of the brain into the empty half of the skull. The dura matter is fastened back into place followed by the top of the skull.
“And there you have it. They'll be a short intermission but we encourage viewers to stay behind to watch the patients wake up.” said Dr. Blaisdell. There is an applause and we make our way out of the operating theatre.

Bill and I are eating small triangles of toast with prawns on them, looking at the throng of people standing in the atrium.
“So the monkey's gonna think they're each other?”
“Yep. And also themselves. I wonder what it must feel like, part of yourself in one body, part of yourself in the other.”
“Must be fucked up.”
“Would you have your brain transplanted into another body?”
“Nope.”
“What about if you were really old, would you put your brain in the body of a teenager?” I ask. Bill thinks for a moment, munching thoughtfully on the appetizer.
“Well, maybe I'd do that. Wouldn't I be an old guy in my head though? What if my body starts growing old, like that Robin Williams film?”
“Benjamin Button?”
“No, he wasn't in that. The other one.”
“Hook? He was Peter Pan in that, that's an old man acting like a kid. He wore tights.”
“Whatever. I dunno about letting Frankenstein poke round in my head is all.” said Bill. I nod. Dr. Blaisdell comes up to us.
“Did you enjoy observing the operation?”
“Yeah, thanks. Ground breaking stuff.” I say.
“It is. Next week we're grafting a nose onto a chimp to see if it would look more human.”
“Chimp with a nose?” said Bill.
“Yeah. We use quite a lot of chimpanzee's for our experiments. All ethical of course.”
“Would you put your brain in a chimp's body?” I ask. Dr. Blaisdell laughs, showing row after row of pearly white teeth.
“Maybe one day. Anyway, I'll see you later. Take care.” he said, walking off. I doubted he would volunteer himself for a human/chimpanzee brain transplant, though maybe he would under the right circumstances. I make a note to pay Dr. Blaisdell a visit later on in the week.

A few hours later we watch the twins slowly wake up.
“Well, they're alive at least.” said Bill.
“Ladies and Gentlemen, welcome to the second part of the afternoon. We will do some basic motor tests and check both hemispheres.” announced Dr. Blaisdell. Assistants helped the chimpanzee's out of their cots and they held hands. A couple of people went 'aww'. Over the next hour we watched the chimpanzee's watch lights flick on or off on either side of their heads.
“They were trained beforehand to press a button when they see a light. This test was first designed by Roger Sperry, though is particularly useful for seeing if the operation was a success with these non-verbal patients.” he said. Up until that point both primates had been separated, though after it was shown both hemispheres appeared to be working correctly they were reintroduced to each other. Or themselves. Everyone was silent as they slowly walked up to each other, making quiet hooting noises.
“Another positive point about using identical twins is that you're used to seeing yourself. They are unaware that their twin is now sharing their skull with them.” said Dr. Blaisdell. The two chimps held each other, making little cooing noises. More people began to fawn and smile. I awaited the point where they would snap, perhaps attacking each other and everyone else. But it didn't come. I signalled to Bill that we should leave and we made our way back onto the Los Angeles street.
“That was nice wasn't it.”
“Yeah, it was alright.” said Bill, getting into the car. I examine his head as we drive back towards my motel, wondering if I would swap brains for a time.